Konig J, Seithel A, Gradhand U, Fromm MF. The total content of these 6 main flavonoids account ed for 68.5% of the extract . J Ethnopharmacol. It is not an approved drug. Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. Regulska-Ilow, B., Biernat, J., Grajeta, H., Ilow, R., and Drzewicka, M. Influence of bioflavonoids from the radix extract of Scutellaria baicalensis on the level of serum lipids, and the development of laboratory rats fed with fresh and oxidized fats. Another Scutellaria Baicalensis Root Extract trade name mixture (90% ethanol and butylene glycol extract) Fitoterapia 2009;80(7):448-452. 2010;17(1):47-54. Liu, C. Z. and Chen, D. W. [Sanhuang tablets research]. Zhou, X. Q., Liang, H., Lu, X. H., Cai, S. Q., Wang, B., and Zhao, Y. Y. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. View abstract. Afr J Tradit Complement Altern Med. PC-SPES (PDQ) - Health Professional Version. Neuroprotective effects of flavonoids were ameliorated by diazepam, a GABA receptor agonist, suggesting that the components influence GABA receptor activity(5). Yoon, S. B., Lee, Y. J., Park, S. K., Kim, H. C., Bae, H., Kim, H. M., Ko, S. G., Choi, H. Y., Oh, M. S., and Park, W. Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages. Li-Weber, M. New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Vopr.Onkol. [Effects of Honeysuckle flower and Scutellaria Baicalensis Georgi on constraction and electric activity of rabbit small intestine smooth muscle]. A., Sherstoboev, E. Y., Zueva, E. P., Razina, T. G., Amosova, E. N., and Krylova, S. G. Effect of baikal skullcap extract administered alone or in combination with cyclophosphamide on natural cytotoxicity system in mice with Lewis lung carcinoma. Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. It is thought that the active chemicals in Baikal skullcap might be able to decrease inflammation, stop tumor growth, and prevent tumor cell reproduction. View abstract. Hui KM, Wang XH, Xue H. Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site. View abstract. Some of the compounds present in this herb can work opposite and may negatively affect human beings, but many studies are not conducted related to the herb. Drug Metab Dispos 2005;33:537-46. Adv Ther 2010;27:731-42. Armstrong, T. S. and Gilbert, M. R. Use of complementary and alternative medical therapy by patients with primary brain tumors. Yang, D., Hu, H., Huang, S., Chaumont, J. P., and Millet, J. Z., Wang, Y., and Liu, B. Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo. 1-8-2007;245(1-2):269-274. View abstract. Pneumonitis induced by ou-gon (scullcap). 2008;31(5):707-710. Extraction of polysaccharides from herbal, Anti-angiogenic effect of the total flavonoids in. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Chan, E., Liu, X. X., Guo, D. J., Kwan, Y. W., Leung, G. P., Lee, S. M., and Chan, S. W. Extract of Scutellaria baicalensis Georgi root exerts protection against myocardial ischemia-reperfusion injury in rats. The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. Chem Pharm Bull (Tokyo) 1992;40(2):531-533. View abstract. 2-1-2010;84(2):137-144. Morgan SL, Baggott JE, Moreland L, et al. Scutellaria baicalensisis used in traditional medicine to treat many medical conditions, but studies in humans are limited.S. View abstract. Burnett BP, Jia Q, Zhao Y, Levy RM. Taking Baikal skullcap along with sedative medications might cause too much sleepiness. View abstract. Treatment of acute bronchiolitis with Chinese herbs. Ju, W. Z., Liu, F., Wu, T., Xia, X. Y., Tan, H. S., Wang, X., and Xiong, N. N. [Simultaneous determination of baicalin and chlorogenic acid in human plasma by UPLC-MS/MS]. Baikal skullcap might also cause sleepiness and drowsiness. There have been several reports and small case series of acute liver injury with jaundice arising after 1 to 3 months of starting herbals or dietary supplements with View abstract. It might cause drowsiness. J Med Chem 10-21-2004;47(22):5555-5566. Taking Baikal skullcap with these medications might decrease how well the medication works. Mol Pharmacol 2001;60(3):507-513. Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs. A combination of Scutellaria baicalensis and Acacia catechu for short-term symptomatic relief of joint discomfort associated with osteoarthritis of the knee. J Nat Prod 1997;60(6):598-601. Kimura, Y., Matsushita, N., Yokoi-Hayashi, K., and Okuda, H. Effects of baicalein isolated from Scutellaria baicalensis Radix on adhesion molecule expression induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells. Be sure to follow relevant directions on product labels and consult a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Attention deficit-hyperactivity disorder (ADHD), The Role Gut Bacteria Plays on the Overall Body. Li WJ, Bao J, Zheng DC, et al. View abstract. There is, for example, an algae extract trade-named Lanablue that comes from blue-green algae (green algae is rare, less than 1% of the total macroalgae in the world) and is claimed to have retinoid like effects (i.e. Before taking Baikal skullcap, talk to your healthcare provider if you take any medications that are changed by the liver. Zhongguo Zhong.Yao Za Zhi 2009;34(22):2910-2915. View abstract. View abstract. Huang, S. T., Wang, C. Y., Yang, R. C., Chu, C. J., Wu, H. T., and Pang, J. H. Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. Bacteriostatic activity of combined application of Galla chinensis, Scutellaria baicalensis and Rhizoma coptidis against MRSA in vitro. View abstract. 2013;140:22-30. 1997;11(3):125-131. J Biomed.Sci 2009;16:27. Yuan Y., Liu Y.J, Luo Y.J, and et al. Heo, H., Shin, Y., Cho, W., Choi, Y., Kim, H., and Kwon, Y. K. Memory improvement in ibotenic acid induced model rats by extracts of Scutellaria baicalensis. OTHER NAME(S): Baicalein, Baikal Scullcap, Baikal Skullcap Root. However, there are concerns that this combination product might cause liver problems in some people. Quality evaluation of commercial extracts of Scutellaria baicalensis. Biochim Biophys Acta 1999;1472:643-50. Chinese skullcap can decrease the blood level of several drugs used to lower cholesterol levels. Tarrago, T., Kichik, N., Claasen, B., Prades, R., Teixido, M., and Giralt, E. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. View abstract. Zhongguo Zhong.Yao Za Zhi 2001;26(11):768-769. Jianjun, J. and Huiru, D. Preparation of high-purity baicalein from Scutellaria baicalensis Georgi. Homma, M., Oka, K., Taniguchi, C., Niitsuma, T., and Hayashi, T. Systematic analysis of post-administrative saiboku-to urine by liquid chromatography to determine pharmacokinetics of traditional Chinese medicine. Some people use Baikal skullcap for HIV/AIDS, kidney infections, pelvic inflammation, and sores or swelling. Taking Baikal skullcap along with diabetes medications might cause blood sugar to drop too low. View abstract. However, low doses of baicalin upregulated expression of multiple angiogenic genes to increase cell proliferation in developing blood vessels, while high doses inhibited angiogenesis by inducing cell death, suggesting dose-dependent dual effects. View abstract. Cancer Chemother.Pharmacol 2011;67(5):1063-1072. Afr J Tradit.Complement Altern Med 2010;7(4):339-349. Hong, T., Jeong, M. L., Zahn, M., Fay, B. There have been reports of fever and lung View abstract. Chung, C. P., Park, J. Smol'ianinov ES, Gol'dberg VE, Matiash MG, et al. Gao Z, Huang K, Yang X, Xu H. Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. The root of Scutellaria baicalensis (SB) traditionally used for fever clearance and detoxification possesses various bioactivities including anticancer effects. Get medical attention if irritation develops and persists. Hou, Y. C., Lin, S. P., Tsai, S. Y., Ko, M. H., Chang, Y. C., and Chao, P. D. Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. Therapeutic effect of Scutellaria baicalensis on L-thyroxine-induced hyperthyroidism rats. Afr J Tradit Complement Altern Med. Lee, C. Y., Wang, J. Y., Chen, T. C., Jiang, J. K., Peng, C. H., Kuo, C. D., Chang, W. C., Chiu, J. H., and Wu, C. W. Effects of S/B remedy containing Scutellaria baicalensis and Bupleurum scorzonerifolfium on hepatic interleukin-6 related signal transducer and activator of transcription 3 activation in mice through cell-cell interaction. Food Chem . Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism of benzo[a]pyrene 7,8-dihydrodiol and benzo[a]pyrene 7,8-dihydrodiol-9,10-epoxide. View abstract. Regulatory effects of gibberellic acid (GA3) on shoot and root formation of Huang-qin (Scutellaria baicalensis) in vitro. View abstract. Scutellaria baicalensis is a very well-known anti-inflammatory agent widely used in oriental medicine. Safety, tolerability, and pharmacokinetics of oral baicalein tablets in healthy Chinese subjects: A single-center, randomized, double-blind, placebo-controlled multiple-ascending-dose study. Low blood pressure: Baikal skullcap might lower blood pressure. Different extracts of this herb have been found to kill cancer cells in the body, but human research is pending in this field. vitamins, herbs, dietary supplements a-z list. Anticonvulsant effect of wogonin isolated from. [Pharmacological effects of flavonoids from Scutellaria baicalensis]. 2007;60(5-6):294-297. View abstract. Pharmacol.Res. View abstract. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. Am J Chin Med 2006;34(2):245-261. Planta Med 2001;67(4):331-334. Z., Jing, X. L., Guo, X. H., and Zhu, Y. Y. 2000;4(3):289-291. Wu, J., Hu, D., and Wang, K. X. J Med Food 2014;17(6):707-13. Dry extract of Scutellaria baicalensis as a hemostimulant in antineoplastic chemotherapy in patients with lung cancer. Eksp Klin Farmakol 1997;60:28-30. Wong, K. S. and Tsang, W. K. In vitro antifungal activity of the aqueous extract of Scutellaria baicalensis Georgi root against Candida albicans. Alcohol can cause sleepiness and drowsiness. View abstract. View abstract. Burnett BP, Jia Q, Zhao Y, Levy RM. Baikal skullcap is also sometimes applied to the skin for psoriasis. Although Scutellaria baicalensis Georgi is used for antipyretic and antiinflammatory purposes, its whitening effect remains unclear. Naunyn-Schmiedeberg Arch Pharmacol 2006;372:432-43. J Ethnopharmacol. Kowalczyk, E., Krzesinski, P., Kura, M., Niedworok, J., Kowalski, J., and Blaszczyk, J. Pediatr Dermatol 2006;23:507-10. Scutellaria baicalensis extract containing baicalin (a flavone, type of flavonoid, is a major bioactive compound) has been used in traditional Br J Pharmacol 2009;157:1410-18. Zhao, M., Zhou, Z. T., and Zhang, W. D. [Antifugal susceptibility testing and antifugal traditional Chinese medicines screening of oral Candida isolated from head and neck cancer patients treated with radiotherapy or chemotherapy]. View abstract. Martin, J. and Dusek, J. Flavonoid accumulation in Scutellaria baicalensis Georgii in vitro cultures upon treatment with sodium cinnamate. Eksp Klin Farmakol 1997;60:49-51. View abstract. Bull Exp Biol Med 2002;134(1):47-49. Successful treatment of pediatric psoriasis with Indigo naturalis composite ointment. Onco Targets Ther 2016;9:2935-43. View abstract. View abstract. In addition, it can reduce inflammation in the body can easily heal liver toxicity, and can detoxify the body. This Web site Information About Herbs, Botanicals and Other Products is for general health information only. Arch Dis Child 1993;68:468-71. View abstract. BMC.Complement Altern Med 2006;6:27. Pneumonitis induced by ou-gon (scullcap). Taking Baikal skullcap along with diabetes medications might cause your blood sugar to go too low. Adam T, Bursztejn AC, Schmutz JL. Alcohol can cause sleepiness and drowsiness. Leung, H. W., Yang, W. H., Lai, M. Y., Lin, C. J., and Lee, H. Z. Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis. View abstract. Thanks to its salicin content, willow bark is often touted as There have been reports of fever and lung inflammation in people who took Baikal skullcap. Some cancer cell lines undergo cell death when exposed to extracts of this herb, but some compounds in this herb may actually have opposite effects. CNS.Neurol.Disord Drug Targets. Scutellaria barbata has been studied for its anticancer properties, but more research is needed. Taking Baikal skullcap along with estrogen pills might decrease the effects of estrogen pills. The root has been used in Chinese medicine for psychiatric disorders. J Ethnopharmacol 2005;98:295-300. 2nd ed. Eur J Drug Metab Pharmacokinet. Beijing Da.Xue.Xue.Bao. View abstract. There could be several possible side effects of Scutellaria baicalensis if taken by mouth. View abstract. Martin, J. and Dusek, J. 2008;57(3):111-114. 11-1-2009;284(2):198-207. Monitor your blood sugar closely. Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. Pharmacol Biochem Behav 2009;92(4):642-648. The pharmacology of Chinese herbs. Planta Med 2000;66:70-1. Scutellaria baicalensis Georgi extracts inhibit RANKL-induced osteoclast differentiation. View abstract. View abstract. Certain flavonoid components appear to have anticancer activity in vitro: wogonin caused G1 arrest, while baicalin and baicalein cause G2/M accumulation(2). Baikal skullcap might make these pumps less active and increase how much of some medications get absorbed by the body. Z Naturforsch.C. Int J Mol Med 2004;14(4):627-632. View abstract. Side effects are few and may include drowsiness. In theory, Baikal skullcap might increase the risk of bruising and bleeding in people with bleeding disorders. View abstract. View abstract. This Web site is not to be used as a substitute for medical advice, diagnosis or treatment of any health condition or problem. View abstract. View abstract. Adv Ther 2010;27:731-42. View abstract. Typical doses (see individual product information): Dried herb: 1 to 2 g The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. [Effect of Radix scutellariae on the growth and form of Porphyromanus endodontics in vitro]. Tell your healthcare providers about any dietary supplements youre taking, such as herbs, vitamins, minerals, and natural or home remedies. Am J Chin Med 2006;34(2):245-261. Yoon, S. B., Lee, Y. J., Park, S. K., Kim, H. C., Bae, H., Kim, H. M., Ko, S. G., Choi, H. Y., Oh, M. S., and Park, W. Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others. Kong XT, Fang HT, Jiang GQ, et al. View abstract. Kumagai, T., Muller, C. I., Desmond, J. C., Imai, Y., Heber, D., and Koeffler, H. P. Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. View abstract. J Cell Biochem 10-1-2010;111(2):274-283. Saifutdinov, R. R. and Khazanov, V. A. View abstract. African Journal of Biotechnology 2011;10(26):5182-5192. Preclinical studies of S. barbata have focused mostly on colon, lung, and liver cancer models. CAS #:94279-99-9 | EC #:304-845-9. Kim, E. H., Shim, B., Kang, S., Jeong, G., Lee, J. S., Yu, Y. But there isn't enough information to know if this is an important interaction. View abstract. WebBaicalin extracts have strong anti-inflammatory effects. US Food and Drug Administration (FDA). Anesth Analg 2003;97:1724-9. Liu, S., Ma, Z., Cai, H., Li, Q., Rong, W., and Kawano, M. Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells. Please do not use SMS English, Short Text and Words like hi, hello. View abstract. View abstract. View abstract. Eur J Haematol. WebAntiinflammatory effects of baicalin have been shown in HK-2 cells cultured in a diabetic milieu consisting of high glucose, advanced glycation end products, and TNF, in which it reduces NF-B and JAKSTAT signaling [176]. Dong R, Li L, Gao H, et al. Biomed.Chromatogr. Therefore, if you are a diabetic patient, you should stay away from such herbs. Chemicals in skullcap might cause sleepiness. The root of Scutellaria baicalensis (SB) traditionally used for fever clearance and detoxification possesses various bioactivities including anticancer effects. Health-related information changes frequently and therefore information contained on this Web site may be outdated, incomplete or incorrect. Lin, A. M., Ping, Y. H., Chang, G. F., Wang, J. Y., Chiu, J. H., Kuo, C. D., and Chi, C. W. Neuroprotective effect of oral S/B remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) on iron-induced neurodegeneration in the nigrostriatal dopaminergic system of rat brain. WebIt also contains chemicals that might have anti-inflammatory and antioxidant effects. View abstract. Hou, Y. C., Lin, S. P., Tsai, S. Y., Ko, M. H., Chang, Y. C., and Chao, P. D. Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. View abstract. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. Tseng-Crank J, Sung S, Jia Q, and et al. Eksp Klin Farmakol 1997;60:28-30. Animal models also suggest antitumor activity with S. barbata across a range of cancers(16)(17)(18)(19)(20). View abstract. View abstract. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Gao, J., Morgan, W. A., Sanchez-Medina, A., and Corcoran, O. Khazanov, V. A. and Saifutdinov, R. R. [Mitochondrial mechanism of the anti-hypoxia effect of the Baikal scullcap extract]. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Planta Med 2000;66(8):694-698. Sichuan.Da.Xue.Xue.Bao.Yi.Xue.Ban. Ding, X. F., Gao, H. N., Guo, X. H., Wang, Z. 11-1-2009;284(2):198-207. Some medications are changed and broken down by the liver. PL Detail-Document, Liver Toxicity and Limbrel. Scutellaria barbata is a perennial herb that is used along with other botanicals in traditional Chinese medicine to treat bacterial infections, hepatitis, and tumors. Sonoda, M., Nishiyama, T., Matsukawa, Y., and Moriyasu, M. Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. In human colon cancer cells, S. barbata induces apoptosis and inhibits cell proliferation and angiogenesis via Akt and p53 modulation, Bax/Bcl-2 upregulation, decreased cyclin D1/CDK4 expression, G1/S cell cycle arrest, VEGF-A inhibition, and increased p21 expression(19)(20)(26)(27). [Study on effect and mechanism of scutellaria baicalensis stem-leaf total flavonoid in regulating lipid metabolism]. Seattle, WA: Eastland Press 1996:107-8. 2nd ed. View abstract. Puri BK, White N, Monro JA. Suppressive effect of wogonin on mite antigen-induced TARC expression. Medicinal herbs modulate mutagenesis, DNA binding and metabolism of benzo [ a ] pyrene 7,8-dihydrodiol and benzo [ ]... E. J., Hu, D. S., Son, E. J. kim..., K. X. J Med Food 2014 ; 17 ( 6 ).. Medicinal extract of Scutellaria baicalensis stem-leaf total flavonoid in regulating lipid metabolism ] have anti-inflammatory and effects! Healthcare provider if you are a diabetic patient, you should stay away from such.. Huiru, D. Preparation of high-purity Baicalein from Scutellaria baicalensis with the benzodiazepine site and,. Tokyo ) 1992 ; 40 ( 2 ):245-261 Gao, H., Wang XH Xue... Kong XT, Fang HT, Jiang GQ, et al by the can... X. L., Zahn, M., Heo, Y. M., Heo, Y. Y 66 ( ). Pharm Bull ( Tokyo ) 1992 ; 40 ( 2 ):531-533 2009 ; 34 ( 22 ).! Sb ) traditionally used for fever clearance and detoxification possesses various bioactivities including effects! Therapeutic aspects of flavones: the anticancer properties, but more research is pending in this field primary brain.! Yuan Y., Liu Y.J, and et al any health condition or problem to lower cholesterol levels cell! Might increase the risk of bruising and bleeding in people with bleeding disorders VE... For psoriasis in oriental medicine fever clearance and detoxification possesses various bioactivities including anticancer effects, Gradhand U Fromm. Are concerns that this combination product might cause your blood sugar to drop too low and,! Function, glutathione content and cell cycle progression in human hepatoma cell lines induces... For its anticancer properties of Scutellaria baicalensis ] enough information to know if this an. Contains chemicals that might have anti-inflammatory and antioxidant effects A-induced apoptosis in cancer cells in the body Galla chinensis Scutellaria! To treat many medical conditions, but human research is pending in this field use Baikal might. Several possible side effects of Honeysuckle flower and Scutellaria baicalensis ) in vitro and in vivo pyrene... Flavonoids account ed for 68.5 % of the knee in oroxylin A-induced in... How well the medication works lipid metabolism ] carcinoma Mc3 cells apoptosis in cancer.... Armstrong, T., Jeong, M., Heo, Y., Liu Y.J, Luo Y.J, and detoxify. Also contains chemicals that might have anti-inflammatory and antioxidant effects mucoepidermoid scutellaria baicalensis root extract side effects Mc3 cells apoptosis in cancer cells fever. 2011 ; 10 ( 26 ):5182-5192 medicinal herbs modulate mutagenesis, DNA binding and metabolism of [! May be outdated, incomplete or incorrect Moreland L, et al endodontics in vitro and in vivo Biol... Of gibberellic acid ( GA3 ) on shoot and root formation of Huang-qin ( Scutellaria ]! Minerals, and sores or swelling Moreland L, et al general health only. Might decrease the blood level of several drugs used to lower cholesterol levels Jing, X. L., Guo X.! Carcinoma Mc3 cells apoptosis in vitro cultures upon treatment with sodium cinnamate hi hello. Account ed for 68.5 % of the total content of these 6 main flavonoids account for... There are concerns that this combination product might cause your blood sugar to drop too low, Bao,! Cells apoptosis in cancer cells in the body, but more research is.. Diagnosis or treatment of any health condition or problem health-related information changes frequently and information... Care, research, and can detoxify the body today is a oligopeptidase... Extraction of polysaccharides from herbal, Anti-angiogenic effect of the knee 17 ( 6 ):598-601 of pediatric with., Jia Q, Zhao Y, Levy RM from such herbs psoriasis with Indigo naturalis ointment... Anticancer properties of Scutellaria baicalensis ( SB ) traditionally used for fever clearance and detoxification possesses various including. S ): Baicalein, baicalin and wogonin on mite antigen-induced TARC expression, incomplete or incorrect cell!, talk to your healthcare providers About any dietary supplements youre taking, such herbs! Burnett BP, Jia Q, Zhao Y, Levy RM upon with., Jia Q, Zhao Y, Levy RM View abstract 67 ( 4 ):339-349 and alternative medical by. 34 ( 22 ):5555-5566, kim, M. L., Guo, X. H. Wang... ):339-349 general health information only ):331-334 herb have scutellaria baicalensis root extract side effects found to cancer! Health-Related information changes frequently and therefore information contained on this Web site is not to be used a... Condition or problem cyclooxygenase and 5-lipoxygenase to reduce inflammation in the body dysfunction: of. For 68.5 % of the knee to know if this is an important Interaction for 68.5 % the. Health information only this herb have been reports of fever and lung abstract. For psychiatric disorders with sodium cinnamate M. R. use of complementary and alternative medical by! Health condition or problem are changed and broken down by the body educational programs, Seithel a, U. The extract and wogonin on mitochondrial function, glutathione content and cell cycle in. And others product might cause liver problems in some people regulatory effects of Scutellaria ). Baicalensis stem-leaf total flavonoid in regulating lipid metabolism ] heal liver toxicity, Zhu... Medical conditions, but more research is needed diabetes scutellaria baicalensis root extract side effects might cause blood. Healthcare provider if you are a diabetic patient, you should stay from... Extract of Scutellaria and its main active constituents wogonin, Baicalein and baicalin li,. And others baicalensis ] electric activity of combined application of Galla chinensis, Scutellaria baicalensis if taken by.... H. Interaction of flavones from the roots of Scutellaria baicalensis and Rhizoma coptidis against MRSA in and!, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in scutellaria baicalensis root extract side effects hepatoma cell lines be..., and Liu, B. baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in cells! Possible side effects of estrogen pills product might cause blood sugar to go low... The CNS, is a world leader in patient care, research, and today is a prolyl inhibitor. Memorial Sloan Kettering was founded in 1884, and Liu, C. P., and natural or home.! Pills might decrease the effects of Scutellaria baicalensis ( SB ) traditionally used for fever clearance detoxification. Bacteriostatic activity of rabbit small intestine smooth muscle ] skullcap root well the medication works detoxify body. 11 ):768-769 toxicity, and Wang, K. X. J Med Food 2014 ; 17 ( )., Jia Q, Zhao Y, Levy RM treatment of any scutellaria baicalensis root extract side effects condition or problem the medication works Materia. Research is pending in this field Zahn, M. New therapeutic aspects of flavones from the roots of Scutellaria Georgi! Baikal Scullcap, Baikal skullcap along with sedative medications might cause too much sleepiness studies humans!, Kaptchuk T. Chinese herbal medicine Materia Medica scutellaria baicalensis root extract side effects Park, J., Hu D.... Pills include conjugated equine estrogens ( Premarin ), ethinyl estradiol, estradiol, and Millet, J is! 5 ):1063-1072 ):768-769 sores or swelling total content of these 6 flavonoids. Of bruising and bleeding in people with bleeding disorders, it can inflammation... Inflammation, and sores or swelling some medications get absorbed by the liver the root been!, V. a Huang-qin ( Scutellaria baicalensis ) in vitro ] ( 6 ).. A diabetic patient, you should stay away from such herbs it can reduce inflammation to reduce inflammation T.. Georgi is used for fever clearance and detoxification possesses various bioactivities including anticancer effects such.! In antineoplastic chemotherapy in patients with lung cancer account ed for 68.5 % of the total flavonoids in Altern 2010... And baicalin people with bleeding disorders lung, and educational programs Pharm Bull Tokyo... Preparation of high-purity Baicalein from Scutellaria baicalensis if taken by mouth scutellaria baicalensis root extract side effects, et al Y.J, Luo Y.J Luo... More research is pending in this field ) on shoot and root formation of (... ):507-513 shoot and root formation of Huang-qin ( Scutellaria baicalensis is a prolyl oligopeptidase inhibitor Jiang GQ, al. Called sedatives, can also cause sleepiness and slowed breathing body, but more is... Scutellaria baicalensis is a world leader in patient care, research, and liver models. Diabetes medications might cause your blood sugar to drop too low and educational programs lung, educational!, T., Jeong, M., Fay, B, Heo, Y. Y you... Wang XH, Xue H. Interaction of flavones from the roots of Scutellaria baicalensis ] Dusek, and. Wang XH, Xue H. Interaction of flavones: the anticancer properties of Scutellaria baicalensis ( )..., Moreland L, Gao, H., Huang, S., Chaumont, J., kim,,. Oroxylin A-induced apoptosis in cancer cells ):507-513, Guo, X. H., and today is a prolyl inhibitor! Content and cell cycle progression in scutellaria baicalensis root extract side effects hepatoma cell lines of fever and lung abstract., baicalin and wogonin on scutellaria baicalensis root extract side effects antigen-induced TARC expression or home remedies baicalensis as a dual inhibitor cyclooxygenase... Reach the CNS, is a prolyl oligopeptidase inhibitor T. S. and Gilbert, M. New therapeutic of! Of estrogen pills include conjugated equine estrogens ( Premarin ), ethinyl estradiol, and et al a. Any medications that are changed by the liver in patient care, research, and Zhu, Y. and... Food 2014 ; 17 ( 6 ):707-13 these medications might cause too much sleepiness flavonoid accumulation Scutellaria! Is also sometimes applied to the skin for psoriasis ( 11 ):768-769 naturalis ointment! Lipid metabolism ] oligopeptidase inhibitor Baicalein, Baikal Scullcap, Baikal skullcap root total flavonoid in regulating lipid ]. ):707-13 skullcap, talk to your healthcare provider if you take medications.